East Sussex - Better Together
NHS

3.3.2 Nebulised Mucolytics

There is no locally commissioned nebuliser service, so patients must self-fund the nebuliser equipment and maintenance costs.

It is essential that patients are assessed as having a strong enough cough to be able to expectorate following nebulisation.

Different strengths of sodium chloride can be used to help clear secretions from the airways.

Dornase alfa and mannitol

Only for use in cystic fibrosis patients; prescribed by the specialist centre.  See chapter 3.5.1 for more information.

This strength may be used in primary care without a challenge test in view of low risk of bronchospasm.

Pack
20 vial

For use where 7% solution is not tolerated and for cases of bronchiolitis.

Suitable for GP prescribing only after challenge testing in secondary care due to risk of significant bronchospasm.

Treatment option for mucus consolidation e.g. in cystic fibrosis, suppurative lung disease, bronchiolitis in adults and children from 6 years.

There is little evidence to support the use of this treatment in the under 6’s.

Pack
20 ampoule

Suitable for GP prescribing only after challenge testing in secondary care due to risk of significant bronchospasm.

Treatment option for mucus consolidation e.g. in cystic fibrosis, suppurative lung disease, bronchiolitis in adults and children from 6 years.

There is little evidence to support the use of this treatment in the under 6’s.

Pack
60 vial

May be used in specialist secondary care services such as Intensive Care and the specialist respiratory wards.

Pack
10 ampoule
  • First Line Drugs
  • Second Line Drugs
  • Specialist Initiated Drugs
  • Specialist Only Drugs
  • Mixed Status