East Sussex - Better Together
NHS

4.7.3 Neuropathic pain

Up to 40% of patients with neuropathic pain may be refractory to drug treatment, so maintaining emotional and physical fitness is important:

  • Offer a choice of amitriptyline, gabapentin or capsaicin as initial treatment for neuropathic pain taking into account individual patient factors (see prescriber decision aid below) and the cost of treatment.
  • If the initial treatment is not effective or is not tolerated, offer one of the remaining drugs, and consider switching again if the second and third drugs tried are also not effective or not tolerated.
  • Pregabalin should normally only be considered following a discussion of treatment options with a pain specialist.

Please see: Prescriber Decision aid for Neuropathic Pain

Resources to support patients living with chronic pain:

NHS Choices: Living with pain

Alternatives to drug treatment:

  • Physiotherapy - important for maintaining function, particularly in complex regional pain syndrome
  • TENS (transcutaneous nerve stimulation) – some patients find this method effective. Machines are available to purchase. TENS is not suitable for patients with pacemakers

NICE CG173: Neuropathic pain

Unlicenced

Pack
45 gram

Licenced for post-herpetic neuralgia and painful diabetic peripheral polyneuropathy

Pack
45 gram

Licensed for diabetic peripheral neuropathic pain only 

Pack
28 capsule
Pack
28 capsule

Licensed for peripheral neuropathic pain only

Pack
100 capsule
Pack
100 capsule
Pack
100 capsule
Pack
100 tablet
  • First Line Drugs
  • Second Line Drugs
  • Specialist Initiated Drugs
  • Specialist Only Drugs
  • Mixed Status