NHS

Lipid regulating drugs

 

Reduction in Low density lipoprotein cholesterol

Dose (mg/day)

5

10

20

40

80

Fluvastatin

-

-

21%1

27%1

33%2

Pravastatin

-

20%1

24%1

29%1

-

Simvastatin

-

27%1

32%2

37%2

42%3,4

Atorvastatin

-

37%2

43%3

49%3

55%3

Rosuvastatin

38%2

43%3

48%3

53%3

-

1 20% - 30%: low intensity

2 31% - 40%: medium intensity

3 above 40%: high intensity

4 Advice from the MHRA: there is an increased risk of myopathy associated with high-dose (80 mg) simvastatin. The 80 mg dose should be considered only in patients with severe hypercholesterolaemia and high risk of cardiovascular complications who have not achieved their treatment goals on lower doses, when the benefits are expected to outweigh the potential risks.

Capsules may be opened for patients with swallowing difficulties

Pack
28 capsule
Pack
28 tablet
30 tablet
90 tablet
Pack
28 capsule
Pack
28 tablet
30 tablet
98 tablet
Pack
28 capsule
Pack
28 tablet
30 tablet
98 tablet
Pack
28 capsule
Pack
28 tablet

MHRA Drug Safety Update: Simvastatin: updated advice on drug interactions

Pack
28 tablet
Pack
28 tablet
  • First Line Drugs
  • Second Line Drugs
  • Specialist Initiated Drugs with Shared Care Guidelines
  • Specialist Only Drugs
  • Mixed Status